According to the documentation, you cannot instantiate buttons except via prefab instantiate.
http://docs.unity3d.com/Manual/HOWTO-UICreateFromScripting.html
You might wonder why we don’t have a API methods to create the various types of controls, including visuals and everything. The reason is that there are an infinite number of way e.g. a button could be setup. Does it use an image, text, or both? Maybe even multiple images? What is the text font, color, font size, and alignment? What sprite or sprites should the image use? By letting you make a prefab and instantiate that, you can set it up exactly the way you want. And if you later want to change the look and feel of your UI you can just change the prefab and then it will be reflected in your UI, including the dynamically created UI.
What I'm trying to do is dynamically create a table of buttons, each one going to a level in my game. The amount of button depends on how many levels the user has unlocked.
I can create a prefab for a button, that's fine, but how do I go about assigning an OnClick event to each of these buttons with an appropriate 'levelIndex' parameter?
I can not find any scripting method to do this, and I'd like to avoid hacky solutions like creating 50 buttons and only showing the first N children.