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comment What does Mecanim's “loop pose” parameter do?
A common use for this check box is in things like movement animations (run cycles, for example) from motion-capture. Unless your mo-cap actor is incredibly consistent in his or her movements, generally the end of a run cycle will not be exactly the same pose as the start of that cycle, so looping it would contain a noticeable pop once per cycle. Checking that box blends the end pose to the start pose, so the run cycle looks seamless.