I'm not experienced in Game Development questions, but as a programmer. In the language Scala, you can have scalable multi-tasking with Actors, very stable, as I hear. You can even have hundreds of thousands of them running at once without a problem.
So I thought, maybe you can use these as a base class for 2D-Sprites, to break out of the game-loop thing that requires to go through all the sprites and move them. They'd basically move themselves, event-driven.
Would that make sense for a game? Having it multitasked like that? After all, it will run on the JVM, though that should not be much of a problem nowadays.
EDIT:
After dabbling for a while, I noticed there is only one real advantage to this idea: Multicore Support. A simple game loop will only run on one core and will work through everything sequentially.
Since modern computers, even at home, nowadays have two or more cores built-in, I think it is a good idea to enable game programmers to efficiently use the other cores. After all, I think usually the player will only have just the game running on his eight-core machine, so why not.
The other advantage I see is that in Scala, you can have RemoteActors, which can be treated the very same way but run on another computer. So maybe this can simplify network gaming as well.
I intend to build that into my Scala 2D engine as soon as I can.